The Ellington Lab conducts research in synthetic biology, protein engineering, and DNA nanotechnology at the University of Texas at Austin.
February 22, 2019: DNA Gets a New — and Bigger — Genetic Alphabet. New York Times
DNA is spelled out with four letters, or bases. Researchers have now built a system with eight. It may hold clues to the potential for life elsewhere in the universe and could also expand our capacity to store digital data on Earth. (Read the full news article or read the paper!)
February 22, 2019: Anna’s project is front page of Nature Chemistry.
The biological function of many proteins requires their assembly into a specific multi-protein structure. Designing artificial protein assemblies is difficult, however, and often relies on the precise redesign of protein–protein interfaces. Now, David W. Taylor, Andrew D. Ellington and colleagues have shown that supercharging green fluorescent protein enables variants of alternating net charge to assemble into a variety of well-defined architectures. The front cover shows a symmetrical 16-mer structure composed of two stacked rings of octamers.
January 18, 2019: A project which the Ellington laboratory is working on is on the news. The UT Austin chemistry team has received a $722,000 NASA grant to establish new methods that show the proof of life outside the Earth.
August 30, 2018: Simple test detects disease-carrying mosquitoes, presence of biopesticide. Sanchitas’ research on Zika is on Science Daily
September 7, 2016: Andre's latest paper on evolving orthogonal suppressor tRNAs for modified amino acid incorporation is now available to read.
July 18 - 21, 2016: Several members of the lab attended SEED 2016 in Chicago, where Andy spoke about the functional incorporation of unnatural amino acids into proteomes.
June 24, 2016: Research by Jared, Jimmy, and Raghav on the development of a reverse transcriptase capable of proofreading is featured in this week's issue of Science.
Summer 2016: Eric Verbeke joins the lab as a summer rotation student. Welcome Eric!
May 25, 2016: Bo's paper on anti-ricin antibody discovery through repertoire analysis and yeast surface display is out.
May 23, 2016: The new lab website is under construction.
April 29, 2016: Jared successfully defends his dissertation.
March 31, 2016: A new paper by Cheulhee on expanding oligonucleotide terminal hairpin formation and self-priming (THSP) by incorporating phosphorothioates is now available.
March 23, 2016: Sherry successfully defends her dissertation.