Generation of protein nanowires
Protein wires can be engineered to alter their nanoelectronic properties
Read MoreMachine learning for protein engineering
The Ellington Lab uses sequence and structure based machine learning models for both de novo design, and protein refinement
Read MoreBiosensing of Clinically Relevant Molecules
We utilize Escherichia coli as a platform for engineering transcription factors that detect small molecules.
Read MoreNon-Canonical Amino Acid Incorporation
The Ellington lab engages in multitude of projects for engineering translational components for the improved incorporation of Non Canonical Amino Acids, both in vitro and in vivo.
Read MoreNovel Opioid Receptor Agonists
The Ellington lab in collaboration with the Marcotte lab have engineered yeast to express mu, delta, and kappa opioid receptors.
Read MoremRNA Capping Enzyme
Developing and improving fusion proteins that combine mRNA capping enzymes and T7 RNA polymerase using synthetic gene circuits and structure-based deep learning models to create systems for dynamic gene regulation in eukaryotic hosts.
Read MoreMicroorganism Based Rare Earth Element Biosensing and Extraction
Several microbes are known to specifically utilize Rare Earth Elements in their metabolisms. We posit that we can leverage those microbes for scalable, environmentally friendly, and non-toxic processing and recycling of Rare Earth Elements.
Read MoreEnzymatic plastic degradation (and upcycling)
The Ellington lab maintains a keen interest in how to best remediate the glut of manmade materials in the environment.
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